Indeed in spite of the fact that the bible tells us that God considers humanity to be the most beautiful of all his creation and even within the show the reason for the fall of Lucifer was his refusal to bow before man. It's quite clear that the distain towards mankind is not just limited to the Lucifer supporters but a general angel thing!

In fact I believe Anna and Castiel are the only angels we've ever met that it can be said truly care for man kind and not just each other or tolerate them for the sake of following God's will!